CCCP
CCCP is a mitochondrial uncoupler that dissipates the proton gradient, inhibiting oxidative phosphorylation. It is widely used in vitro to study mitochondrial function, cellular metabolism, and innate immunity, as it also suppresses the STING-TBK1-IRF3 signaling pathway.
Product Specifications
CAS Number
555-60-2
Product Name Alternative
CCCP, Apoptosis, Bacterial, Carbonyl Cyanide m-Chlorophenylhydrazone, Carbonyl cyanide 3-chlorophenylhydrazone, MPYS, IkB, IkB/IKK, IKK, IκB, inhibit, MitochondrialMetabolism, MITA, Mitochondrial Metabolism, ERIS, IFN-β, IFNAR, Inhibitor, Interferon-α/β receptor, Interferon-alpha/beta receptor, TBK1, Stimulator of Interferon Genes, STING, TMEM173
Field of Research
Cell Biology, Immunology & Inflammation, Infectious Disease & Virology, Metabolism Research, Neuroscience, Signal Transduction
Purity
97.15% (May vary between batches)
Solubility
Ethanol:5 mg/mL (24.44 mM) ; DMSO:252.5 mg/mL (1233.99 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:6 mg/mL (29.32 mM)
Smiles
ClC1=CC=CC (N\N=C (/C#N) C#N) =C1
Molecular Formula
C9H5ClN4
Molecular Weight
204.62
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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