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Cytochalasin B

Cytochalasin B is a fungal metabolite that potently inhibits actin polymerization by capping the barbed ends of filaments (Kd ~1.4-2.2 nM) . It is widely used in cell biology research to study cytoskeletal dynamics, cell motility, and processes like cytokinesis in both in vitro and cellular assays.

Product Specifications

CAS Number

14930-96-2

Product Name Alternative

NSC107658; Phomin

Field of Research

Cardiovascular Research, Cell Biology

Purity

>98%

Bioactivity

Actin filament disrupting agent

Form

Powder

Solubility

Soluble in DMSO (up to 5 mg/ml) or in Ethanol (up to 10 mg/ml) .

Smiles

[H][C@]12[C@H] (Cc3ccccc3) NC (=O) C11OC (=O) \C=C\[C@H] (O) CCC[C@@H] (C) C\C=C\[C@@]1 ([H]) [C@H] (O) C (=C) [C@H]2C

Molecular Formula

C29H37NO5

Molecular Weight

479.6

Storage Conditions

-20°C

Notes

For research use only.

Other Product Names

Fermentation product from Drechslera dematioidea

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