Navarixin
Navarixin (MK-7123/SCH527123) is a selective CXCR2 antagonist that blocks neutrophil activation and migration. It is a research tool for studying neutrophilic inflammation in models of pulmonary diseases such as COPD and asthma, with demonstrated effects in both in vitro and in vivo experimental systems.
Product Specifications
CAS Number
473727-83-2
Product Name Alternative
SCH 527123, SCH527123, SCH-527123, CXC chemokine receptors, CXCR2, CXCR1, CXCR, Inhibitor, inhibit, MK 7123, MK7123, MK-7123, Navarixin
Field of Research
Cell Biology, Immunology & Inflammation, Pharmacology & Drug Discovery
Purity
98.00% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.03 mM) ; DMSO:55 mg/mL (138.39 mM)
Smiles
CC[C@@H] (Nc1c (Nc2cccc (C (=O) N (C) C) c2O) c (=O) c1=O) c1ccc (C) o1
Molecular Formula
C21H23N3O5
Molecular Weight
397.42
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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