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S29434

S29434 (NMDPEF) is a potent and competitive inhibitor of quinone reductase 2 (QR2), exhibiting activity in the low nanomolar range (IC50: 5-16 nM) . This small molecule is a valuable research tool for studying QR2's role in metabolic processes and oxidative stress, with applications in both in vitro biochemical assays and in vivo pharmacological models.

Product Specifications

CAS Number

874484-20-5

Product Name Alternative

Selective, Quinone reductase 2, S29434, S-29434, S 29434, ROS, memory, Inhibitor, HepG2, NMDPEF, mice, inhibit, cell-permeable, Autophagy

Field of Research

Cell Biology, Metabolism Research

Purity

99.92% (May vary between batches)

Solubility

DMSO:12.5 mg/mL (33.39 mM) ;10% DMSO+40% PEG300+5% Tween-80+45% Saline:1 mg/mL (2.67 mM)

Smiles

COc1ccc2n3Cc4cccnc4-c3c (CCNC (=O) c3ccco3) c2n1

Molecular Formula

C21H18N4O3

Molecular Weight

374.39

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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