GSK2982772
GSK2982772 is a potent and selective RIPK1 inhibitor, demonstrating IC50 values of 16 nM (human) and 20 nM (monkey) . This small molecule is a valuable research tool for investigating RIPK1-mediated necroptosis and inflammation in both cellular and animal models of inflammatory and neurodegenerative diseases.
Product Specifications
CAS Number
1622848-92-3
Product Name Alternative
Receptor-interacting protein kinases, RIP kinase, RIP1, RIPK, RIPkinase, inhibit, Inhibitor, GSK2982772, GSK-2982772, GSK 2982772
Field of Research
Cell Biology
Purity
>98%
Bioactivity
Highly selective RIPK1 inhibitor
Form
Powder
Solubility
Soluble in DMSO (up to 25 mg/ml)
Smiles
CN1c2ccccc2OC[C@H] (NC (=O) c2n[nH]c (Cc3ccccc3) n2) C1=O
Molecular Formula
C20H19N5O3
Molecular Weight
377.4
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
(S) -5-Benzyl-N- (5-methyl-4-oxo-2,3,4,5-tetrahydrobenzo[b]-[1,4]oxazepin-3-yl) -4H-1,2,4-traizole-3-carboxamide
Available Sizes
Frequently Asked Questions
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