NIBR189
NIBR189 is a potent and selective EBI2 (GPR183) receptor antagonist, exhibiting IC50 values of 11 nM and 15 nM for human and mouse receptors, respectively. This tool compound is used in vitro and in vivo to investigate the role of EBI2 in immune cell migration and inflammatory diseases.
Product Specifications
CAS Number
1599432-08-2
Product Name Alternative
Small molecule, U937, autoimmune, autoimmune diseases, EBI2, EBI2/GPR183, GPR183, G protein, mice, migration, NIBR 189, NIBR189, NIBR-189, inhibit, Inhibitor
Field of Research
Infectious Disease & Virology, Pharmacology & Drug Discovery
Purity
97.00% (May vary between batches)
Solubility
DMSO:47 mg/mL (109.48 mM) ;10% DMSO+90% Corn Oil:2 mg/mL (4.66 mM)
Smiles
COc1ccc (cc1) C (=O) N1CCN (CC1) C (=O) \C=C\c1ccc (Br) cc1
Molecular Formula
C21H21BrN2O3
Molecular Weight
429.31
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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