Purvalanol B
Purvalanol B is a potent and selective ATP-competitive inhibitor of cyclin-dependent kinases (CDKs), including Cdk2/cyclin A, Cdk2/cyclin E, Cdk5/p35, and Cdk2/cyclin B with IC50 values in the single-digit nanomolar range. This cell-permeable compound is widely used in biochemical and cellular research to study cell cycle progression, neuronal function, and apoptosis in various cancer and neurobiology models.
Product Specifications
CAS Number
212844-54-7
Product Name Alternative
Parasite, NG95, NG-95, NG 95, inhibit, Inhibitor, CDK5, CDK, CDK2, cdc2, Cyclin dependent kinase, cyclin, ATP, P. falciparum, p35, Purvalanol B
Field of Research
Cell Biology, Infectious Disease & Virology
Purity
98.00% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.62 mM) ; DMSO:40 mg/mL (92.4 mM)
Smiles
CC (C) [C@H] (CO) Nc1nc (Nc2ccc (C (O) =O) c (Cl) c2) c2ncn (C (C) C) c2n1
Molecular Formula
C20H25ClN6O3
Molecular Weight
432.9
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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