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CZC-8004

CZC-8004 is a multi-targeted tyrosine kinase inhibitor with potent activity against ABL kinase. It is utilized in biochemical and cellular assays to study kinase signaling pathways and has been employed in preclinical research for investigating oncogenic mechanisms in relevant in vitro models.

Product Specifications

CAS Number

916603-07-1

Product Name Alternative

Epidermal growth factor receptor, EGFR, ErbB-1, Inhibitor, HER1, inhibit, CZC 00008004, CZC 8004, CZC00008004, CZC-00008004, CZC8004, CZC-8004, aminopyrimidine, BcrAbl, Bcr-Abl, Abl, tyrosine kinases, VEGFR, Vascular endothelial growth factor receptor

Field of Research

Cardiovascular Research, Signal Transduction

Purity

>98%

Bioactivity

Multi-kinase inhibitor; Affinity ligand

Form

Powder

Solubility

Soluble in DMSO (up to 30 mg/ml) or in Ethanol (up to 2.5 mg/ml with warming)

Smiles

NCc1ccc (Nc2ncc (F) c (Nc3ccccc3) n2) cc1

Molecular Formula

C17H16FN5

Molecular Weight

309.33

Storage Conditions

-20°C

Notes

For research use only.

Other Product Names

N2-[4- (Aminomethyl) phenyl]-5-fluoro-N4-phenyl-2,4-[yrimidinediamine

Available Sizes

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