DL-Buthionine- (S, R) -sulfoximine
DL-Buthionine- (S, R) -sulfoximine (BSO) is a potent and selective inhibitor of γ-glutamylcysteine synthetase, the rate-limiting enzyme in glutathione biosynthesis. It is widely used in cancer research, both in vitro and in vivo, to deplete cellular glutathione and study oxidative stress mechanisms in solid tumor models.
Product Specifications
CAS Number
5072-26-4
Product Name Alternative
γ-glutamylcysteine synthetase, Ferroptosis, Inhibitor, inhibit, NSC 381100, NSC381100, NSC-381100, BSO, Buthionine sulfoximine, Butionine sulfoximine, D, L-Buthionine- (S, R) -sulfoximine, D, L-Buthionine-sulfoximine, DLButhionine (S, R) sulfoximine, DL-Buthionine-sulfoximine, DL Buthionine (S, R) sulfoximine
Field of Research
Cell Biology
Purity
98.00% (May vary between batches)
Solubility
H2O:31.25 mg/mL (140.57 mM) ; DMSO:Insoluble
Smiles
CCCCS (=N) (=O) CCC (N) C (O) =O
Molecular Formula
C8H18N2O3S
Molecular Weight
222.31
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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