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DL-Buthionine- (S, R) -sulfoximine

DL-Buthionine- (S, R) -sulfoximine (BSO) is a potent and selective inhibitor of γ-glutamylcysteine synthetase, the rate-limiting enzyme in glutathione biosynthesis. It is widely used in cancer research, both in vitro and in vivo, to deplete cellular glutathione and study oxidative stress mechanisms in solid tumor models.

Product Specifications

CAS Number

5072-26-4

Product Name Alternative

γ-glutamylcysteine synthetase, Ferroptosis, Inhibitor, inhibit, NSC 381100, NSC381100, NSC-381100, BSO, Buthionine sulfoximine, Butionine sulfoximine, D, L-Buthionine- (S, R) -sulfoximine, D, L-Buthionine-sulfoximine, DLButhionine (S, R) sulfoximine, DL-Buthionine-sulfoximine, DL Buthionine (S, R) sulfoximine

Field of Research

Cell Biology

Purity

98.00% (May vary between batches)

Solubility

H2O:31.25 mg/mL (140.57 mM) ; DMSO:Insoluble

Smiles

CCCCS (=N) (=O) CCC (N) C (O) =O

Molecular Formula

C8H18N2O3S

Molecular Weight

222.31

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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