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H3B-6527

H3B-6527 is a potent, selective FGFR4 inhibitor developed for FGF19-driven hepatocellular carcinoma research. It demonstrates antineoplastic activity in both in vitro cell-based assays and in vivo xenograft models, making it a key tool for studying targeted HCC therapies.

Product Specifications

CAS Number

1702259-66-2

Product Name Alternative

H3B 6527, H3B6527, H-3B-6527, H3B-6527, FGFR

Field of Research

Cardiovascular Research, Signal Transduction

Purity

97.45% (May vary between batches)

Solubility

DMSO:6.3 mg/mL (10.01 mM)

Smiles

CCN1CCN (CC1) c1ccc (Nc2cc (ncn2) N (C) C (=O) Nc2c (Cl) c (OC) cc (OC) c2Cl) c (NC (=O) C=C) c1

Molecular Formula

C29H34Cl2N8O4

Molecular Weight

629.54

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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