H3B-6527
H3B-6527 is a potent, selective FGFR4 inhibitor developed for FGF19-driven hepatocellular carcinoma research. It demonstrates antineoplastic activity in both in vitro cell-based assays and in vivo xenograft models, making it a key tool for studying targeted HCC therapies.
Product Specifications
CAS Number
1702259-66-2
Product Name Alternative
H3B 6527, H3B6527, H-3B-6527, H3B-6527, FGFR
Field of Research
Cardiovascular Research, Signal Transduction
Purity
97.45% (May vary between batches)
Solubility
DMSO:6.3 mg/mL (10.01 mM)
Smiles
CCN1CCN (CC1) c1ccc (Nc2cc (ncn2) N (C) C (=O) Nc2c (Cl) c (OC) cc (OC) c2Cl) c (NC (=O) C=C) c1
Molecular Formula
C29H34Cl2N8O4
Molecular Weight
629.54
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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