Thalidomide 4-fluoride
Thalidomide 4-fluoride is a Cereblon (CRBN) -directed E3 ligase ligand used to construct PROTAC molecules, such as PROTAC IRAK4 degrader-1. This compound enables targeted protein degradation, facilitating the study of IRAK4 signaling pathways in both cellular and biochemical research contexts.
Product Specifications
CAS Number
835616-60-9
Product Name Alternative
Inhibit, IRAK4, Ligand for E3 Ligase, LigandforE3Ligase, Ligands for E3 Ligase, Inhibitor, Cereblon ligand4, Cereblon ligand 4, Cereblon ligand-4, E3 ligase Ligand 4, E3 ligase-recruiting Moiety, Thalidomide 4fluoride, Thalidomide 4-fluoride, Thalidomide, Thalidomide 4 fluoride
Field of Research
Cell Biology, Immunology & Inflammation, Pharmacology & Drug Discovery, Signal Transduction
Purity
99.12% (May vary between batches)
Solubility
DMSO:199 mg/mL (720.44 mM)
Smiles
O=C1N (C (=O) C=2C1=CC=CC2F) C3C (=O) NC (=O) CC3
Molecular Formula
C13H9FN2O4
Molecular Weight
276.22
Storage Conditions
-20°C
Notes
For research use only.
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