Pomalidomide-PEG4-Ph-NH2
This synthetic conjugate features a pomalidomide-based cereblon ligand connected via a tetraethylene glycol (PEG4) linker, terminating in a phenylamine group. It serves as a key component in the development of PROTACs for targeted protein degradation, a technique widely applied in both in vitro and in vivo cancer and disease mechanism research.
Product Specifications
CAS Number
1818885-63-0
Product Name Alternative
Inhibitor, inhibit, LigandforE3Ligase, Ligand for E3 Ligase, E3 Ligase Ligand Linker Conjugates 2, E3 Ligase Ligand-Linker Conjugates, E3 Ligase LigandLinker Conjugates 2, E3 Ligase Ligand-Linker Conjugates 2, Cereblon Ligand-Linker Conjugates 9, Pomalidomide-PEG4-Ph-NH2
Field of Research
Pharmacology & Drug Discovery
Purity
95.42% (May vary between batches)
Solubility
H2O:< 0.1 mg/mL (insoluble) ; DMSO:50 mg/mL (92.49 mM)
Smiles
O=C1C=2C (C (=O) N1C3C (=O) NC (=O) CC3) =CC=CC2NCCOCCOCCOCCOC4=CC=C (N) C=C4
Molecular Formula
C27H32N4O8
Molecular Weight
540.57
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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