CCG-222740
CCG-222740 is a potent and selective small molecule inhibitor targeting the Rho/MRTF signaling pathway. It is utilized in research to investigate fibrotic diseases, cancer metastasis, and vascular remodeling in both cellular and animal models.
Product Specifications
CAS Number
1922098-69-8
Product Name Alternative
Muscle, myocardin-related, inhibit, MRTF, Inhibitor, metastasis, orally, melanoma, fibrosis, expression, factor, CCG 222740, actin, alpha-smooth, CCG222740, CCG-222740, Rho, Rho-associated kinase, Rho-associated protein kinase, Rho-kinase, ROK, ROCK, protein, Ras, transcription
Field of Research
Cell Biology, Pharmacology & Drug Discovery, Signal Transduction, Stem Cell & Developmental Biology
Purity
98.76% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (8.99 mM) ; DMSO:125 mg/mL (280.99 mM)
Smiles
FC1 (F) CC (CN (C1) C (=O) c1cccc (c1) -c1ccco1) C (=O) Nc1ccc (Cl) cc1
Molecular Formula
C23H19ClF2N2O3
Molecular Weight
444.86
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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