DRB
DRB is a nucleoside analog that acts as a potent inhibitor of multiple carboxyl-terminal domain (CTD) kinases, notably casein kinase II, with IC50 values ranging from 4 to 10 μM. It is widely used in biochemical and cellular research to study transcription regulation, RNA polymerase II activity, and cell cycle progression in both in vitro and in vivo experimental models.
Product Specifications
CAS Number
53-85-0
Product Name Alternative
5,6-Dichlorobenzimidazole riboside; NSC 401575
Field of Research
Cell Biology, Infectious Disease & Virology, Protein Biochemistry
Purity
>98%
Bioactivity
Transcription inhibitor; CK2 inhibitor
Form
Powder
Solubility
Soluble in DMSO (up to 20 mg/ml)
Smiles
C1=C2C (=CC (=C1Cl) Cl) N (C=N2) [C@H]3[C@@H] ([C@@H] ([C@H] (O3) CO) O) O
Molecular Formula
C12H12Cl2N2O4
Molecular Weight
319.14
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
5,6-Dichloro-1-β-D-ribofuranosylbenzimidazole
Available Sizes
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