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Alloxan monohydrate

Alloxan monohydrate is a proteasome inhibitor used to induce experimental diabetes models. It selectively damages pancreatic β-cells, impairing insulin secretion. This compound is widely applied in diabetes research for establishing both in vivo animal models and in vitro β-cell toxicity studies.

Product Specifications

CAS Number

2244-11-3

Product Name Alternative

Insulin, Inhibitor, inhibit, diabetes, diabetogenic agent, Alloxan, Alloxan monohydrate, Alloxan Monohydrate, 26S, 20S proteasomes, B cells, Proteasome

Field of Research

Protein Biochemistry

Purity

99.01% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (12.49 mM) ; DMSO:60 mg/mL (374.79 mM)

Smiles

O.O=C1NC (=O) C (=O) C (=O) N1

Molecular Formula

C4H4N2O5

Molecular Weight

160.09

Storage Conditions

-20°C

Notes

For research use only.

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