PT-2385
PT-2385 is a potent and selective small molecule inhibitor of HIF-2α, exhibiting a dissociation constant (Kd) below 50 nM. It is a valuable research tool for studying hypoxia signaling pathways in both cellular and animal models, particularly in oncology and renal physiology research.
Product Specifications
CAS Number
1672665-49-4
Product Name Alternative
Inhibit, Inhibitor, Hypoxia-inducible factors, HIFProlylHydroxylase, HIFs, HIF ProlylHydroxylase, HIF Prolyl-Hydroxylase, HIF, HIF/HIFProlylHydroxylase, HIF/HIF ProlylHydroxylase, HIF/HIF Prolyl-Hydroxylase, HIF-PH, HIF-2α, PT 2385, PT2385, PT-2385
Field of Research
Cardiovascular Research, Epigenetics & Chromatin, Metabolism Research
Purity
98.69% (May vary between batches)
Solubility
DMSO:270 mg/mL (704.34 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.22 mM)
Smiles
CS (=O) (=O) c1ccc (Oc2cc (F) cc (c2) C#N) c2CC (F) (F) [C@@H] (O) c12
Molecular Formula
C17H12F3NO4S
Molecular Weight
383.34
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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