Flumatinib mesylate
Flumatinib mesylate is a potent and selective small molecule inhibitor targeting c-Abl, PDGFRβ, and c-Kit tyrosine kinases. It has demonstrated efficacy in overcoming resistance conferred by specific KIT mutations in preclinical studies, supporting its investigation in related hematological and solid tumor research both in vitro and in vivo.
Product Specifications
CAS Number
895519-91-2
Product Name Alternative
CD117, cKit, c-Kit, c-Abl, BcrAbl, Bcr-Abl, inhibit, Platelet-derived growth factor receptor, Flumatinib, Flumatinib Mesylate, Flumatinib mesylate, Inhibitor, HHGV 678, HHGV 678 Mesylate, HHGV678, HHGV-678, HHGV678 mesylate, HHGV678 Mesylate, HHGV-678 Mesylate, SCFR, PDGFR, PDGFRβ
Field of Research
Cardiovascular Research, Signal Transduction
Purity
99.82% (May vary between batches)
Solubility
DMSO:70 mg/mL (106.27 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.04 mM) ; H2O:50 mg/mL (75.91 mM)
Smiles
CS (O) (=O) =O.CN1CCN (Cc2ccc (cc2C (F) (F) F) C (=O) Nc2cnc (C) c (Nc3nccc (n3) -c3cccnc3) c2) CC1
Molecular Formula
C30H33F3N8O4S
Molecular Weight
658.69
Storage Conditions
-20°C
Notes
For research use only.
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