IOX4
IOX4 is a highly potent and selective inhibitor of prolyl hydroxylase domain protein 2 (PHD2/EGLN1) with an IC50 of 1.6 nM. It is widely used in hypoxia-related research to stabilize HIF-α in vitro and has been applied in studies investigating ischemic and inflammatory disease models in vivo.
Product Specifications
CAS Number
1154097-71-8
Product Name Alternative
HIF-PH, HIFProlylHydroxylase, HIFs, Hypoxia-inducible factors, HIF ProlylHydroxylase, HIF, HIF Prolyl-Hydroxylase, HIF/HIF ProlylHydroxylase, HIF/HIF Prolyl-Hydroxylase, HIF/HIFProlylHydroxylase, Inhibitor, inhibit, IOX 4, IOX4, IOX-4, PHD2
Field of Research
Epigenetics & Chromatin, Metabolism Research
Purity
98.87% (May vary between batches)
Solubility
DMSO:83.33 mg/mL (253.8 mM)
Smiles
CC (C) (C) OC (=O) c1ccc (nc1) -n1[nH]cc (-n2ccnn2) c1=O
Molecular Formula
C15H16N6O3
Molecular Weight
328.33
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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