SP-13786
SP-13786 is a potent dual inhibitor of fibroblast activation protein (FAP; IC50 = 3.2 nM) and prolyl oligopeptidase (PREP; IC50 = 1.8 μM) . This small molecule is a valuable research tool for investigating the roles of these enzymes in fibrosis, cancer, and neurological disorders in both cellular and animal models.
Product Specifications
CAS Number
1448440-52-5
Product Name Alternative
FAP, SP 13786, SP13786, SP-13786, UAMC1110, UAMC-1110, UAMC 1110
Field of Research
Immunology & Inflammation, Metabolism Research, Protein Biochemistry
Purity
97.96% (May vary between batches)
Solubility
DMSO:250 mg/mL (726.07 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (11.62 mM)
Smiles
C (NCC (=O) N1[C@H] (C#N) CC (F) (F) C1) (=O) C=2C3=C (N=CC2) C=CC=C3
Molecular Formula
C17H14F2N4O2
Molecular Weight
344.32
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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