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PBD-150

PBD-150 is a potent small molecule inhibitor of the human glutaminyl cyclase (hQC) Y115E-Y117E mutant, exhibiting an inhibition constant (Ki) of 490 nM. This compound is a valuable research tool for investigating hQC's role in vitro, particularly in studies related to neurodegenerative conditions where QC activity is implicated.

Product Specifications

CAS Number

790663-33-1

Product Name Alternative

Beta Amyloid, BetaAmyloid, bAmyloid, b Amyloid, Amyloid-β, Abeta, Alzheimer, glutaminyl cyclase (hQC) Y115E-Y117E, PBD 150, PBD150, PBD-150, Inhibitor, inhibit, βAmyloid, β Amyloid, β-amyloid peptide

Field of Research

Neuroscience

Purity

>98%

Bioactivity

Glutaminyl cyclase inhibitor

Form

Powder

Solubility

Soluble in DMSO (up to at least 25 mg/ml) or in Ethanol (up to at least 25 mg/ml)

Smiles

COc1ccc (NC (=S) NCCCn2ccnc2) cc1OC

Molecular Formula

C15H20N4O2S

Molecular Weight

320.4

Storage Conditions

-20°C

Notes

For research use only.

Other Product Names

1- (3,4-Dimethoxyphenyl) -3-93-imidazol-1-ylpropyl) thiourea

Available Sizes

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