PBD-150
PBD-150 is a potent small molecule inhibitor of the human glutaminyl cyclase (hQC) Y115E-Y117E mutant, exhibiting an inhibition constant (Ki) of 490 nM. This compound is a valuable research tool for investigating hQC's role in vitro, particularly in studies related to neurodegenerative conditions where QC activity is implicated.
Product Specifications
CAS Number
790663-33-1
Product Name Alternative
Beta Amyloid, BetaAmyloid, bAmyloid, b Amyloid, Amyloid-β, Abeta, Alzheimer, glutaminyl cyclase (hQC) Y115E-Y117E, PBD 150, PBD150, PBD-150, Inhibitor, inhibit, βAmyloid, β Amyloid, β-amyloid peptide
Field of Research
Neuroscience
Purity
>98%
Bioactivity
Glutaminyl cyclase inhibitor
Form
Powder
Solubility
Soluble in DMSO (up to at least 25 mg/ml) or in Ethanol (up to at least 25 mg/ml)
Smiles
COc1ccc (NC (=S) NCCCn2ccnc2) cc1OC
Molecular Formula
C15H20N4O2S
Molecular Weight
320.4
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
1- (3,4-Dimethoxyphenyl) -3-93-imidazol-1-ylpropyl) thiourea
Available Sizes
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