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Mobocertinib

Mobocertinib (TAK-788) is a selective, small-molecule EGFR inhibitor developed as an antineoplastic agent. It is utilized in preclinical and clinical research, particularly for targeting EGFR exon 20 insertion mutations in non-small cell lung cancer models, both in vitro and in vivo.

Product Specifications

CAS Number

1847461-43-1

Product Name Alternative

CUTO14, AP32788, AP-32788, AP 32788, A431, Mobocertinib, NSCLC, LU0387, Inhibitor, inhibit, ErbB-1, Epidermal growth factor receptor, EGFRex20ins, EGFR, H1975, HER1, HCC4011, HCC827, tak788, TAK-788, TAK 788

Field of Research

Cardiovascular Research, Signal Transduction

Purity

98.66% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (1.71 mM) ; DMSO:5 mg/mL (8.54 mM)

Smiles

COc1cc (N (C) CCN (C) C) c (NC (=O) C=C) cc1Nc1ncc (C (=O) OC (C) C) c (n1) -c1cn (C) c2ccccc12

Molecular Formula

C32H39N7O4

Molecular Weight

585.7

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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