PNU112455A hydrochloride
PNU112455A hydrochloride is a competitive ATP-binding site inhibitor of CDK2 and CDK5, exhibiting Km values of 3.6 μM and 3.2 μM, respectively. This small molecule is a research tool for studying cell cycle regulation and neuronal function in vitro, with applications in oncology and neurodegenerative disease research.
Product Specifications
CAS Number
21886-12-4
Product Name Alternative
Site, PNU112455A, PNU-112455A hydrochloride, PNU 112455A, PNU 112455A HCL, anticooperative, ATP, Alzheimer's, CDK
Field of Research
Cell Biology
Purity
98.58% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (13.26 mM) ; DMSO:125 mg/mL (414.25 mM)
Smiles
Cl.Nc1cc (Nc2ccc (cc2) S (N) (=O) =O) ncn1
Molecular Formula
C10H12ClN5O2S
Molecular Weight
301.75
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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