BRD3308
BRD3308 is a potent and selective HDAC3 inhibitor with an IC50 of 54 nM. It specifically reduces phenylephrine-induced ERK phosphorylation without affecting JNK, making it a valuable chemical probe for studying HDAC3 function in cardiac hypertrophy and fibrosis research in vitro.
Product Specifications
CAS Number
1550053-02-5
Product Name Alternative
β-cells, inflammatory, inhibit, Inhibitor, hyperglycaemia, Human immunodeficiency virus, insulin, HDAC, HDAC3, HIV, HIV Protease, HIVProtease, HIV-1, Histone deacetylases, latency, glucolipotoxicity, Apoptosis, diabetes, cytokines, BRD3308, BRD-3308, BRD 3308
Field of Research
Cell Biology, Epigenetics & Chromatin, Infectious Disease & Virology, Molecular Biology, Protein Biochemistry
Purity
97.00% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (6.96 mM) ; DMSO:52 mg/mL (181 mM)
Smiles
CC (=O) Nc1ccc (cc1) C (=O) Nc1ccc (F) cc1N
Molecular Formula
C15H14FN3O2
Molecular Weight
287.29
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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