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BRD3308

BRD3308 is a potent and selective HDAC3 inhibitor with an IC50 of 54 nM. It specifically reduces phenylephrine-induced ERK phosphorylation without affecting JNK, making it a valuable chemical probe for studying HDAC3 function in cardiac hypertrophy and fibrosis research in vitro.

Product Specifications

CAS Number

1550053-02-5

Product Name Alternative

β-cells, inflammatory, inhibit, Inhibitor, hyperglycaemia, Human immunodeficiency virus, insulin, HDAC, HDAC3, HIV, HIV Protease, HIVProtease, HIV-1, Histone deacetylases, latency, glucolipotoxicity, Apoptosis, diabetes, cytokines, BRD3308, BRD-3308, BRD 3308

Field of Research

Cell Biology, Epigenetics & Chromatin, Infectious Disease & Virology, Molecular Biology, Protein Biochemistry

Purity

97.00% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (6.96 mM) ; DMSO:52 mg/mL (181 mM)

Smiles

CC (=O) Nc1ccc (cc1) C (=O) Nc1ccc (F) cc1N

Molecular Formula

C15H14FN3O2

Molecular Weight

287.29

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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