ONO-7475
ONO-7475 is a selective small molecule inhibitor targeting the AXL and MER (MERTK) tyrosine kinases. It is a valuable research tool for studying oncogenic signaling in cancer models, demonstrating activity in both in vitro cellular assays and in vivo studies related to leukemia and solid tumors.
Product Specifications
CAS Number
1646839-59-9
Product Name Alternative
Acute, advanced, Axl, cancer, EGFR, Inhibitor, Mer, leukemia, inhibit, mutunt, lung, metastatic, NSCLC, ONO 7475, ONO7475, ONO-7475, TAMReceptor, TAM Receptor, solid, tolerant, TKI, tumor, Tyro3, Tropomyosin related kinase receptor, Trk receptor, Trk Receptor, Trkreceptor
Field of Research
Signal Transduction
Purity
98.33% (May vary between batches)
Solubility
DMSO:100 mg/mL (177.76 mM) ;10% DMSO+40% PEG300+5% Tween-80+45% Saline:1 mg/mL (1.78 mM)
Smiles
COc1cc2nccc (Oc3ccc (NC (=O) c4cc5C (=O) CCCc5n (-c5ccccc5) c4=O) nc3) c2cc1OC
Molecular Formula
C32H26N4O6
Molecular Weight
562.57
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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