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BIO-013077-01

BIO-013077-01 is a small molecule antagonist that potently inhibits TGFβ family type I receptors, including ALK4, ALK5, and ALK7. It is a valuable research tool for studying TGFβ signaling in cancer, fibrosis, and immunology, with demonstrated utility in both cellular assays and in vivo disease models.

Product Specifications

CAS Number

746667-48-1

Product Name Alternative

Inhibit, fibrosis, Inhibitor, BIO 013077 01, BIO01307701, BIO-013077-01, autophosphorylation, Alkylation, ALK5, Transforming growth factor beta receptors, TGFbeta/Smad, TGFbeta, TGF-beta, TGFβ, TGF-β/Smad, TGF-β Receptor, TGF-b/Smad, TGFb, Smad, pyrazoles

Field of Research

Stem Cell & Developmental Biology

Purity

99.87% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (3.48 mM) ; DMSO:10 mg/mL (34.8 mM)

Smiles

Cc1cccc (n1) -c1n[nH]cc1-c1ccc2nccnc2c1

Molecular Formula

C17H13N5

Molecular Weight

287.32

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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