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CADD522

CADD522 (MFCD00167693) is a potent small molecule inhibitor that disrupts RUNX2-DNA binding with an IC50 of 10 nM. It exhibits antitumor activity and is a valuable research tool for studying RUNX2 function in cancer biology, bone metastasis, and osteosarcoma in both cellular and animal models.

Product Specifications

CAS Number

199735-88-1

Product Name Alternative

Reactive Oxygen Species, T47D-RUNX2, runt-related transcription factor-2 (RUNX2) -DNA, inhibit, MFCD00167693, MFCD-00167693, MFCD 00167693, Inhibitor, MDA-231, MDA-468, MCF7, CADD 522, CADD522, CADD-522, breast cancer

Field of Research

Immunology & Inflammation, Metabolism Research, Signal Transduction

Purity

95.81% (May vary between batches)

Solubility

DMSO:245 mg/mL (751.14 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (15.33 mM)

Smiles

OC (=O) C1C2CC (C=C2) C1C (=O) NC1=CC=C (Cl) C (Cl) =C1

Molecular Formula

C15H13Cl2NO3

Molecular Weight

326.17

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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