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OGG1-IN-08

OGG1-IN-08 is a potent and selective small molecule inhibitor of 8-oxoguanine DNA glycosylase 1 (OGG1), exhibiting an IC50 of 0.35 μM. This inhibitor is a valuable chemical probe for investigating the role of OGG1 and the base excision repair pathway in oxidative stress-related research, including studies in cellular and animal models of inflammation, cancer, and neurodegeneration.

Product Specifications

CAS Number

350997-39-6

Product Name Alternative

AP site, 8-oxoguanine DNA glycosylase 1 (OGG1), lyase, OGG1, OGG1 IN 08, OGG1IN08, OGG-1-IN-08, OGG1-IN-08, OGG1-IN-O8, inhibit, Inhibitor, glycosylase, FapyGua

Field of Research

Epigenetics & Chromatin

Purity

96.12% (May vary between batches)

Solubility

DMSO:27.5 mg/mL (105.31 mM)

Smiles

NNC (=O) C1=C (Cl) C2=C (Cl) C=CC=C2S1

Molecular Formula

C9H6Cl2N2OS

Molecular Weight

261.13

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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