OGG1-IN-08
OGG1-IN-08 is a potent and selective small molecule inhibitor of 8-oxoguanine DNA glycosylase 1 (OGG1), exhibiting an IC50 of 0.35 μM. This inhibitor is a valuable chemical probe for investigating the role of OGG1 and the base excision repair pathway in oxidative stress-related research, including studies in cellular and animal models of inflammation, cancer, and neurodegeneration.
Product Specifications
CAS Number
350997-39-6
Product Name Alternative
AP site, 8-oxoguanine DNA glycosylase 1 (OGG1), lyase, OGG1, OGG1 IN 08, OGG1IN08, OGG-1-IN-08, OGG1-IN-08, OGG1-IN-O8, inhibit, Inhibitor, glycosylase, FapyGua
Field of Research
Epigenetics & Chromatin
Purity
96.12% (May vary between batches)
Solubility
DMSO:27.5 mg/mL (105.31 mM)
Smiles
NNC (=O) C1=C (Cl) C2=C (Cl) C=CC=C2S1
Molecular Formula
C9H6Cl2N2OS
Molecular Weight
261.13
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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