ML210
ML-210 is a potent, selective, and covalent GPX4 inhibitor (EC50=30 nM) . It is a research tool used to induce ferroptosis, a form of regulated cell death, and has demonstrated antitumor activity in both cellular and in vivo cancer models.
Product Specifications
CAS Number
1360705-96-9
Product Name Alternative
Covalent, CID 49766530, CID49766530, CID-49766530, anti-cancer, inhibit, ML210, ML-210, ML 210, Inhibitor, Ferroptosis, GlutathionePeroxidase, GPX4, Gpx4, glutathione, Glutathione Peroxidase, Ras, peroxidase, selenocysteine, residue
Field of Research
Cell Biology
Purity
>98%
Bioactivity
GPX4 inhibitor; Ferroptosis Inducer
Form
Powder
Solubility
Soluble in DMSO (up to 30 mg/ml)
Smiles
Cc1onc (C (=O) N2CCN (CC2) C (c2ccc (Cl) cc2) c2ccc (Cl) cc2) c1[N+] ([O-]) =O
Molecular Formula
C22H20Cl2N4O4
Molecular Weight
475.3
Storage Conditions
RT
Notes
For research use only.
Other Product Names
(4- (Bis (4-chlorophenyl) methyl) piperazine-1-yl) (5-methyl-4-nitroisoxazol-3-yl) methanone
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