RO2959 Hydrochloride
RO2959 Hydrochloride is a selective CRAC channel inhibitor with an IC50 of 402 nM and a potent suppressor of human IL-2 production. This compound is a valuable research tool for studying T-cell activation and calcium signaling in both cellular and animal models of immune dysfunction.
Product Specifications
CAS Number
1219927-22-6
Product Name Alternative
CRAC Channel, CRAC channel, CalciumChannel, Calcium Channel, Calcium release-activated channels, Ca2+ release-activated Ca2+ channels, anti-proliferation, failure, heart, Inhibitor, Interleukin Related, Interleukin, IL Receptor, Orai1, inhibit, ILReceptor, IL-2, IP3, RO 2959, RO 2959 Hydrochloride, RO2959, RO-2959, RO2959 HCl, RO2959 Hydrochloride, RO-2959 Hydrochloride, SOCE, Stim1, T-cell
Field of Research
Immunology & Inflammation, Metabolism Research, Pharmacology & Drug Discovery
Purity
97.42% (May vary between batches)
Solubility
DMSO:10 mg/mL (21.55 mM)
Smiles
Cl.Cc1cnc (s1) N1CCC (C) =C (C1) c1cnc (NC (=O) c2c (F) cccc2F) cn1
Molecular Formula
C21H20ClF2N5OS
Molecular Weight
463.93
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
38852151 3x 1.0 µg DNA
RFC2 CRISPR All-in-one AAV vector set (with saCas9)(Human)
Sign In for Pricing
View Details 
MBS6184246-01 0.1 mL
FUT7 (Fucosyltransferase 7 (alpha (1,3) Fucosyltransferase), FucT-VII) (PE)
Sign In for Pricing
View Details MBS6184246-02 5x 0.1 mL
FUT7 (Fucosyltransferase 7 (alpha (1,3) Fucosyltransferase), FucT-VII) (PE)
Sign In for Pricing
View Details 
