(Rac) -JBJ-04-125-02
JBJ-04-125-02 demonstrates efficacy as a monotherapy in EGFR-mutant lung cancer models, both in vitro and in vivo. This small molecule inhibitor is a research tool for studying oncogenic EGFR signaling and evaluating potential therapeutic strategies in preclinical cancer research.
Product Specifications
CAS Number
2140807-05-0
Product Name Alternative
Anti-proliferation, anti-tumor, (Rac) JBJ 04 125 02, (Rac) JBJ0412502, Allosteric, EGFR, EGFR (L858R/T790M), Epidermal growth factor receptor, ErbB-1, Inhibitor, HER1, inhibit, JBJ-04-125-02, T790M-mutant, racemate
Field of Research
Cardiovascular Research, Signal Transduction
Purity
95.85% (May vary between batches)
Solubility
DMSO:55 mg/mL (101.18 mM)
Smiles
Oc1ccc (F) cc1C (N1Cc2ccc (cc2C1=O) -c1ccc (cc1) N1CCNCC1) C (=O) Nc1nccs1
Molecular Formula
C29H26FN5O3S
Molecular Weight
543.61
Storage Conditions
-20°C
Notes
For research use only.
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