CD73-IN-3
CD73-IN-3 (LY-3475070) is a potent and selective CD73 inhibitor with an IC50 of 28 nM. It is utilized in immuno-oncology research to study adenosine-mediated immunosuppression in tumor microenvironments, both in vitro and in preclinical in vivo models, often in combination with immune checkpoint inhibitors.
Product Specifications
CAS Number
2375815-63-5
Product Name Alternative
Cancer, CD73, CD73 IN 3, CD73IN3, CD-73-IN-3, CD73-IN-3, EX-A4254, EX-A-4254, EX-A 4254, inhibit, Inhibitor, Immunosuppression, LY 3475070, LY3475070, LY-3475070, tumor
Field of Research
Immunology & Inflammation
Purity
99.59% (May vary between batches)
Solubility
DMSO:22.5 mg/mL (78.58 mM)
Smiles
[H][C@@]1 (C[C@@H]1C (C) C) c1cc (nnc1C) -c1c[nH]c (=O) [nH]c1=O
Molecular Formula
C15H18N4O2
Molecular Weight
286.33
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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