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CD73-IN-3

CD73-IN-3 (LY-3475070) is a potent and selective CD73 inhibitor with an IC50 of 28 nM. It is utilized in immuno-oncology research to study adenosine-mediated immunosuppression in tumor microenvironments, both in vitro and in preclinical in vivo models, often in combination with immune checkpoint inhibitors.

Product Specifications

CAS Number

2375815-63-5

Product Name Alternative

Cancer, CD73, CD73 IN 3, CD73IN3, CD-73-IN-3, CD73-IN-3, EX-A4254, EX-A-4254, EX-A 4254, inhibit, Inhibitor, Immunosuppression, LY 3475070, LY3475070, LY-3475070, tumor

Field of Research

Immunology & Inflammation

Purity

99.59% (May vary between batches)

Solubility

DMSO:22.5 mg/mL (78.58 mM)

Smiles

[H][C@@]1 (C[C@@H]1C (C) C) c1cc (nnc1C) -c1c[nH]c (=O) [nH]c1=O

Molecular Formula

C15H18N4O2

Molecular Weight

286.33

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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