PFM01
PFM01 is a small molecule inhibitor of the MRE11 endonuclease, enabling researchers to modulate the cellular DNA double-strand break repair pathway choice. It suppresses homologous recombination (HR) and can promote error-prone non-homologous end joining (NHEJ), making it a valuable tool for studying DNA repair mechanisms in cancer research and cellular response to genotoxic agents both in vitro and in vivo.
Product Specifications
CAS Number
1558598-41-6
Product Name Alternative
PFM 01, PFM01, PFM-01, endonuclease, inhibit, Inhibitor, MRE11, N-alkylated, NHEJ, Mirin, derivative, DSB
Field of Research
Cell Biology
Purity
98.68% (May vary between batches)
Solubility
DMSO:4 mg/mL (13.63 mM)
Smiles
CC (C) CN1C (=S) S\C (=C/c2ccc (O) cc2) C1=O
Molecular Formula
C14H15NO2S2
Molecular Weight
293.4
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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