PFM01
PFM01 is a small molecule inhibitor of the MRE11 endonuclease, enabling researchers to modulate the cellular DNA double-strand break repair pathway choice. It suppresses homologous recombination (HR) and can promote error-prone non-homologous end joining (NHEJ), making it a valuable tool for studying DNA repair mechanisms in cancer research and cellular response to genotoxic agents both in vitro and in vivo.
Product Specifications
CAS Number
1558598-41-6
Product Name Alternative
PFM 01, PFM01, PFM-01, endonuclease, inhibit, Inhibitor, MRE11, N-alkylated, NHEJ, Mirin, derivative, DSB
Field of Research
Cell Biology
Purity
98.68% (May vary between batches)
Solubility
DMSO:4 mg/mL (13.63 mM)
Smiles
CC (C) CN1C (=S) S\C (=C/c2ccc (O) cc2) C1=O
Molecular Formula
C14H15NO2S2
Molecular Weight
293.4
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
![Rabbit Monoclonal TC-PTP/PTPN2 Antibody (001) [Alexa Fluor 750]](https://cdn.genprice.uk/genprice/uk/genprice2.webp)
NBP2-90722AF750 0.1 mL
Rabbit Monoclonal TC-PTP/PTPN2 Antibody (001) [Alexa Fluor 750]
Sign In for Pricing
View Details 
K7108406 1.0 µg DNA
Synrg sgRNA CRISPR/Cas9 All-in-One Lentivector (Rat) (Target 1)
Sign In for Pricing
View Details