YUM70
YUM70 is a potent and selective GRP78 inhibitor (IC50 = 1.5 μM) that induces ER stress and apoptosis in pancreatic cancer cells. It serves as a valuable chemical probe for studying ER stress mechanisms and apoptosis in both in vitro and in vivo cancer research models.
Product Specifications
CAS Number
423145-35-1
Product Name Alternative
Apoptosis, cancer, Heat shock proteins, Inhibitor, glucose-regulated, GRP78, HSP, endoplasmic, inhibit, pancreatic, stress-mediated, reticulum, protein, YUM 70, YUM70, YUM-70
Field of Research
Cell Biology, Metabolism Research, Pharmacology & Drug Discovery, Signal Transduction
Purity
97.25% (May vary between batches)
Solubility
DMSO:100 mg/mL (250.73 mM)
Smiles
CCCC (=O) NC (c1ccc2OCOc2c1) c1cc (Cl) c2cccnc2c1O
Molecular Formula
C21H19ClN2O4
Molecular Weight
398.84
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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