BC1618
BC1618 is an orally bioavailable small molecule inhibitor of Fbxo48 that activates AMPK signaling. This compound induces mitochondrial fission and autophagy, leading to improved hepatic insulin sensitivity in research models, making it a useful tool for studying metabolism and metabolic diseases.
Product Specifications
CAS Number
2222094-18-8
Product Name Alternative
E1 activating enzyme, E3 Enzyme, E2Enzyme, E2 Enzyme, E2 conjugating enzyme, E1Enzyme, E1 Enzyme, E1/E2/E3 Enzyme, E3 ligating enzyme, E3Enzyme, 2-Propanol, 1-[bis (phenylmethyl) amino]-3-[4- (trifluoromethyl) phenoxy]-, AMPK, AMP-activated protein kinase, BC1618, BC-1618, BC 1618, LPS, Inhibitor, inhibit, mTORC, mitochondrial, Mitochondrial Autophagy, Mitophagy, metformin, pAmpk, insulin, Fbxo48, fission, pS6, Ubiquitin activating enzyme, Ubiquitin ligase, Ubiquitin conjugating enzyme
Field of Research
Cell Biology, Epigenetics & Chromatin, Protein Biochemistry, Signal Transduction
Purity
99.09% (May vary between batches)
Solubility
DMSO:100 mg/mL (240.7 mM) ;10% DMSO+90% Corn Oil:3.3 mg/mL (7.94 mM)
Smiles
OC (COc1ccc (cc1) C (F) (F) F) CN (Cc1ccccc1) Cc1ccccc1
Molecular Formula
C24H24F3NO2
Molecular Weight
415.45
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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