ICCB-19 hydrochloride
ICCB-19 hydrochloride is a small molecule inhibitor that targets the TRADD-N domain, disrupting its interaction with TRAF2 and TRADD-C. This inhibition modulates RIPK1 and beclin 1 ubiquitination, making it a useful research tool for studying TNF signaling, apoptosis, and autophagy in cellular models.
Product Specifications
CAS Number
1803605-68-6
Product Name Alternative
RIPkinase, RIPK, RIP kinase, RIPK1, ubiquitination, TRADD, RDA, Receptor-interacting protein kinases, k63, inhibit, Inhibitor, ICCB 19, ICCB 19 hydrochloride, ICCB 19 Hydrochloride, ICCB19, ICCB-19, ICCB-19 HCl, ICCB-19 HCl (750621-52-4 free base), ICCB19 Hydrochloride, ICCB19 hydrochloride, ICCB-19 Hydrochloride, beclin1, Apoptosis, Autophagy, 750621-52-4, 750621-52-4 free base, cIAP2, cIAP1
Field of Research
Cell Biology, Signal Transduction
Purity
99.23% (May vary between batches)
Solubility
DMSO:25 mg/mL (85.66 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (6.85 mM)
Smiles
Cl.O=C (CSC1=NCCN1) NC1CCCCCC1
Molecular Formula
C12H22ClN3OS
Molecular Weight
291.84
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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