(6R) -FR054
(6R) -FR054 is a potent and selective small molecule inhibitor of PGM3, a key enzyme in the Hexosamine Biosynthetic Pathway (HBP) . It demonstrates significant anti-proliferative activity against breast cancer cells in vitro and has shown efficacy in reducing tumor growth in vivo models, making it a valuable chemical probe for oncology and metabolic pathway research.
Product Specifications
CAS Number
10378-06-0
Product Name Alternative
Breast, Apoptosis, cancer, (6R) FR054, (6R) FR054, (6R) -FR054, (6R) -FR-054, ERS, FR054, FR-054, FR 054, Inhibitor, inhibit, PGM3, TNBC
Field of Research
Cell Biology
Purity
99.61% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (12.15 mM) ; DMSO:100 mg/mL (303.67 mM)
Smiles
[H][C@@]12OC (C) =N[C@]1 ([H]) [C@@H] (OC (C) =O) [C@@H] (OC (C) =O) [C@@H] (COC (C) =O) O2
Molecular Formula
C14H19NO8
Molecular Weight
329.3
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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