GW280264X
GW280264X is a potent and selective small molecule inhibitor of ADAM17 (TACE) . It is widely used in biochemical and cellular research to investigate the protease's role in ectodomain shedding of TNF-α and other substrates in both in vitro and in vivo models.
Product Specifications
CAS Number
866924-39-2
Product Name Alternative
TACE, stem, Matrix metalloproteinases, immunogenicity, GIC, glioblastoma, GW280264X, GW-280264X, immunotherapy, inhibit, Inhibitor, MMP, Mixed, metalloproteinases, ADAM17, ADAM10, Carbamic acid
Field of Research
Protein Biochemistry
Purity
99.51% (May vary between batches)
Solubility
10% DMSO+90% Corn Oil:1 mg/mL (1.74 mM) ; DMSO:11 mg/mL (19.11 mM)
Smiles
CCC[C@@H] ([C@@H] (CC (C) C) C (=O) N[C@@H] (CCCCNC (=O) OCc1ccccc1) C (=O) Nc1nccs1) N (O) C=O
Molecular Formula
C28H41N5O6S
Molecular Weight
575.72
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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