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PD-089828

PD 089828 is a potent small molecule inhibitor targeting key tyrosine kinases. It acts as a competitive inhibitor of FGFR1, PDGFRβ, and EGFR, and a noncompetitive inhibitor of c-Src. This compound is a valuable research tool for studying kinase signaling in cancer and angiogenesis, applicable in both cellular and biochemical assays.

Product Specifications

CAS Number

179343-17-0

Product Name Alternative

Src, smooth, Platelet-derived growth factor receptor, PDGFR, PDGFRβ, phosphorylation, vascular, PD089828, PD-089828, PD 089828, muscle, nonselective, inhibit, Inhibitor, HER1, EGFR, Epidermal growth factor receptor, Fibroblast growth factor receptor, FGFR1, FGFR, ErbB-1, cells, competitive, autophosphorylation, ATP, antimigratory, antiproliferative

Field of Research

Cardiovascular Research, Signal Transduction

Purity

96.78% (May vary between batches)

Solubility

DMSO:< 1 mg/mL (insoluble or slightly soluble)

Smiles

CC (C) (C) NC (=O) Nc1nc2nc (N) ncc2cc1-c1c (Cl) cccc1Cl

Molecular Formula

C18H18Cl2N6O

Molecular Weight

405.28

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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