PD-089828
PD 089828 is a potent small molecule inhibitor targeting key tyrosine kinases. It acts as a competitive inhibitor of FGFR1, PDGFRβ, and EGFR, and a noncompetitive inhibitor of c-Src. This compound is a valuable research tool for studying kinase signaling in cancer and angiogenesis, applicable in both cellular and biochemical assays.
Product Specifications
CAS Number
179343-17-0
Product Name Alternative
Src, smooth, Platelet-derived growth factor receptor, PDGFR, PDGFRβ, phosphorylation, vascular, PD089828, PD-089828, PD 089828, muscle, nonselective, inhibit, Inhibitor, HER1, EGFR, Epidermal growth factor receptor, Fibroblast growth factor receptor, FGFR1, FGFR, ErbB-1, cells, competitive, autophosphorylation, ATP, antimigratory, antiproliferative
Field of Research
Cardiovascular Research, Signal Transduction
Purity
96.78% (May vary between batches)
Solubility
DMSO:< 1 mg/mL (insoluble or slightly soluble)
Smiles
CC (C) (C) NC (=O) Nc1nc2nc (N) ncc2cc1-c1c (Cl) cccc1Cl
Molecular Formula
C18H18Cl2N6O
Molecular Weight
405.28
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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