NSC45586
NSC45586 is a selective small molecule inhibitor of the protein phosphatases PHLPP1 and PHLPP2. It is a valuable research tool for studying the Akt and PKC signaling pathways in cancer biology, utilized in both cellular and in vivo experimental models.
Product Specifications
CAS Number
6300-44-3
Product Name Alternative
PP2C, PHLPP, PHLPP1, PHLPP2, Inhibitor, NSC 45586, inhibit, NSC-45586, NSC45586, pleckstrin homology domain and leucine-rich repeat protein phosphatase, AKT
Field of Research
Protein Biochemistry, Signal Transduction
Purity
95.09% (May vary between batches)
Solubility
Ethanol:Insoluble; H2O:Insoluble; DMSO:82 mg/mL (198.36 mM)
Smiles
CC1=CC (=C (C=C1N) N) N=NC2=CC=C (C=C2) N=NC3=CC (=C (C=C3) O) C (=O) O.[Na+]
Molecular Formula
C20H18N6NaO3+
Molecular Weight
413.4
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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