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HPK1-IN-2

HPK1-IN-2 is a potent, orally bioavailable small molecule inhibitor of Hematopoietic Progenitor Kinase 1 (HPK1), also inhibiting Lck and Flt3. It demonstrates antitumor activity and is a valuable chemical probe for researching HPK1 signaling in immunology and oncology, applicable in both in vitro and in vivo experimental models.

Product Specifications

CAS Number

2056122-11-1

Product Name Alternative

Thieno[2,3-b]pyridin-6 (7H) -one, 4-amino-5-[6- (4-methyl-1-piperazinyl) -1H-benzimidazol-2-yl]-HPK1-IN-2, HPK1, HPK1 IN 2 dihydrochloride, HPK1-IN-2, HPK1-IN-2, HPK1IN2 dihydrochloride, HPK-1-IN-2 dihydrochloride, Lck, Flt3

Field of Research

Cardiovascular Research, Signal Transduction

Purity

97.31% (May vary between batches)

Solubility

H2O:25 mg/mL (65.71 mM)

Smiles

NC1=C (C=2NC=3C (N2) =CC=C (C3) N4CCN (C) CC4) C (=O) NC5=C1C=CS5

Molecular Formula

C19H20N6OS

Molecular Weight

380.47

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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