HPK1-IN-2
HPK1-IN-2 is a potent, orally bioavailable small molecule inhibitor of Hematopoietic Progenitor Kinase 1 (HPK1), also inhibiting Lck and Flt3. It demonstrates antitumor activity and is a valuable chemical probe for researching HPK1 signaling in immunology and oncology, applicable in both in vitro and in vivo experimental models.
Product Specifications
CAS Number
2056122-11-1
Product Name Alternative
Thieno[2,3-b]pyridin-6 (7H) -one, 4-amino-5-[6- (4-methyl-1-piperazinyl) -1H-benzimidazol-2-yl]-HPK1-IN-2, HPK1, HPK1 IN 2 dihydrochloride, HPK1-IN-2, HPK1-IN-2, HPK1IN2 dihydrochloride, HPK-1-IN-2 dihydrochloride, Lck, Flt3
Field of Research
Cardiovascular Research, Signal Transduction
Purity
97.31% (May vary between batches)
Solubility
H2O:25 mg/mL (65.71 mM)
Smiles
NC1=C (C=2NC=3C (N2) =CC=C (C3) N4CCN (C) CC4) C (=O) NC5=C1C=CS5
Molecular Formula
C19H20N6OS
Molecular Weight
380.47
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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