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JHU37160

JHU37160 is a potent and selective DREADD agonist, exhibiting high affinity and efficacy at both hM3Dq and hM4Di receptors. This tool compound is widely used in neuroscience research for the chemogenetic manipulation of specific neuronal circuits in both in vitro cellular assays and in vivo animal models to study behavior and neural function.

Product Specifications

CAS Number

2369979-68-8

Product Name Alternative

Clozapine, DREADD, M3 mAChR, mAChR, Inhibitor, Muscarinic acetylcholine receptor, JHU37160, JHU-37160, JHU 37160, inhibit, hM3Dq, hM4Di

Field of Research

Neuroscience

Purity

99.25% (May vary between batches)

Solubility

DMSO:72 mg/mL (200.65 mM) ; Ethanol:72 mg/mL (200.65 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.57 mM)

Smiles

CCN1CCN (CC1) C1=Nc2cc (Cl) ccc2Nc2c (F) cccc12

Molecular Formula

C19H20ClFN4

Molecular Weight

358.84

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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